Description

4-Chloropicolinic Acid Hydrochloride is a high-purity organic salt derivative of picolinic acid, serving as a crucial synthetic intermediate in advanced chemical manufacturing. Its value lies in providing a reactive halogenated pyridine scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality building blocks for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the chloropyridine moiety is a critical functional group.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new heterocyclic chemistry and developing novel synthetic methodologies.
• Material Science Precursor: Can be utilized in the synthesis of functionalized polymers or organic electronic materials that require specific pyridine-based monomers.

Basic Information

Product Name	4-Chloropicolinic Acid Hydrochloride
CAS No.	1036648-06-2
Molecular Formula	C6H5Cl2NO2
Molecular Weight	194.02 g/mol
Synonyms	4-Chloro-2-pyridinecarboxylic acid hydrochloride; 4-Chloropyridine-2-carboxylic acid hydrochloride; Picolinic acid, 4-chloro-, hydrochloride; 2-Carboxy-4-chloropyridine hydrochloride; 4-Chloropicolinic acid HCl salt
EINECS	Contact for details

Quality Control

Our 4-Chloropicolinic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.