Description

7H-Spiro(Furo(3,4-B)Pyridine-5,4'-Piperidine) is a high-value, spirocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its unique fused-ring structure makes it a versatile building block for constructing complex molecules with potential biological activity. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its spirocyclic scaffold.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for potential new chemical entities (NCEs).
• Library Synthesis for High-Throughput Screening: Employed to create focused libraries of diverse, drug-like compounds for biological screening.
• Academic Research: Used in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	7H-Spiro(Furo(3,4-B)Pyridine-5,4'-Piperidine)
CAS No.	1036408-86-2
Molecular Formula	C12H14N2O
Molecular Weight	202.25 g/mol
Synonyms	7H-Spiro[furo[3,4-b]pyridine-5,4'-piperidine]; 7H-Spiro(furo(3,4-b)pyridine-5,4'-piperidine); Furo[3,4-b]pyridine, 7H-spiro-5,4'-piperidine-; 1036408-86-2; Spiro[furo[3,4-b]pyridine-5,4'-piperidine]; 7H-Spiro(furo(3,4-B)pyridine-5,4'-piperidine)
EINECS	Contact for details

Quality Control

Our 7H-Spiro(Furo(3,4-B)Pyridine-5,4'-Piperidine) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.