Description

3-Aminocyclobutanol Hydrochloride is a versatile and high-purity chemical building block essential for advanced organic synthesis. This compound is valued for its unique strained cyclobutane ring functionalized with both amino and hydroxyl groups, making it a critical intermediate in pharmaceutical research and development. It is primarily used by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to create novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry: Used in scaffold hopping and structure-activity relationship (SAR) studies to explore new chemical space.
• Peptidomimetics: Serves as a constrained amino acid analog for designing bioactive peptides with enhanced metabolic stability.
• Agrochemical Research: Intermediate in the development of new herbicides and pesticides with novel modes of action.
• Ligand Synthesis: Precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Used to create tool compounds for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Aminocyclobutanol Hydrochloride
CAS No.	1036260-25-9
Molecular Formula	C4H10ClNO
Molecular Weight	123.58 g/mol
Synonyms	3-Aminocyclobutanol HCl; 3-Amino-1-hydroxycyclobutane Hydrochloride; Cyclobutanol, 3-amino-, hydrochloride; 1-Hydroxy-3-aminocyclobutane Hydrochloride; 3-Aminocyclobutyl Alcohol Hydrochloride; 3-Hydroxycyclobutanamine Hydrochloride; (3-Hydroxycyclobutyl)amine Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Aminocyclobutanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.