Description

1-(5-Methoxy-1,3-Benzoxazol-2-Yl)Piperidine-3-Carboxylic Acid is a high-purity, non-natural amino acid derivative featuring a benzoxazole-piperidine scaffold. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents. The structural motif offers significant potential for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: The carboxylic acid and heterocyclic structure make it a candidate for designing inhibitors of specific enzymes.
• Ligand Synthesis: Used in the development of novel ligands for biological targets such as GPCRs or ion channels.
• Chemical Biology Probes: Employed in the creation of tool compounds for investigating biological pathways and protein function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	1-(5-Methoxy-1,3-Benzoxazol-2-Yl)Piperidine-3-Carboxylic Acid
CAS No.	1035840-45-9
Molecular Formula	C15H18N2O4
Molecular Weight	290.32 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-(5-methoxy-2-benzoxazolyl)-; 1-(5-Methoxybenzo[d]oxazol-2-yl)piperidine-3-carboxylic acid; 5-Methoxy-2-(3-carboxypiperidin-1-yl)benzoxazole; 1035840-45-9; UNII-9K8Z9F8F2M; 9K8Z9F8F2M; AKOS025147065; AS-64111; SCHEMBL15506227; DTXSID90648669
EINECS	Contact for details

Quality Control

Our 1-(5-Methoxy-1,3-Benzoxazol-2-Yl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is compatible with strong acid/organic solvent environments but should be kept separate from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.