Description

[Rucl(p-Cymene)((R)-Tolbinap)]Cl is a chiral ruthenium(II) complex, specifically designed as a high-performance asymmetric catalyst. This compound matters for its ability to facilitate highly enantioselective transformations, a critical requirement for producing optically pure intermediates in advanced synthesis. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for the development of new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Enables the production of chiral building blocks for APIs with high optical purity.
• Fine Chemical Manufacturing: Used in the synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.
• Methodology Development: A valuable tool for chemists in academic and industrial R&D for developing new catalytic asymmetric reactions.
• Process Chemistry Optimization: Employed in scaling up enantioselective routes from laboratory to pilot plant scale.

Basic Information

Product Name	[Rucl(p-Cymene)((R)-Tolbinap)]Cl
CAS No.	1034001-51-8
Molecular Formula	C₅₈H₅₂ClP₂Ru
Molecular Weight	942.41 g/mol
Synonyms	RuCl(p-cymene)[(R)-TolBINAP]; Dichloro(p-cymene)ruthenium(II) dimer with (R)-TolBINAP; (R)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl (p-cymene)ruthenium(II) chloride; (R)-TolBINAP-Ru(p-cymene)Cl complex; Ru-TolBINAP catalyst; Chiral Ru(II)-arene complex; Asymmetric hydrogenation catalyst Ru-TolBINAP
EINECS	Contact for details

Quality Control

Every batch of [Rucl(p-Cymene)((R)-Tolbinap)]Cl is characterized and tested to ensure consistent catalytic performance and purity. Our quality assurance includes identity confirmation via spectroscopic methods and purity assessment to meet the stringent requirements of process chemistry and R&D. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and residual solvent levels is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to maintain stability and prevent oxidation. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% ee
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.