Description

cis-Tetrahydrofuran-3,4-Diamine Dihydrochloride is a high-purity, versatile chiral diamine building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and sophisticated ligands for catalysis. It is primarily needed by research chemists and process development scientists in pharmaceutical R&D, agrochemical manufacturing, and fine chemical production for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Ligand Synthesis: Serves as a precursor for constructing chiral ligands used in asymmetric catalysis, such as hydrogenation and C-C bond-forming reactions.
• Agrochemical Development: Used in the research and production of advanced, enantiomerically pure pesticides and herbicides.
• Fine Chemical Building Block: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical control.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and material science laboratories.

Basic Information

Product Name	cis-Tetrahydrofuran-3,4-Diamine Dihydrochloride
CAS No.	1033712-94-5
Molecular Formula	C4H10N2O · 2HCl
Molecular Weight	187.07 g/mol
Synonyms	(3R,4S)-3,4-Diaminotetrahydrofuran Dihydrochloride; (3S,4R)-3,4-Diaminotetrahydrofuran Dihydrochloride; cis-3,4-Diaminotetrahydrofuran Dihydrochloride; Tetrahydro-3,4-furandiamine Dihydrochloride; 3,4-Diaminotetrahydrofuran Dihydrochloride; THF-3,4-diamine Dihydrochloride; 3,4-Diaminofuranidine Dihydrochloride
EINECS	Contact for details

Quality Control

Our cis-Tetrahydrofuran-3,4-Diamine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.