Description

Imidazo[1,2-A]Pyridine, 6-Chloro-8-Iodo- is a high-value halogenated heterocyclic building block with the CAS registry number 1033463-28-3. This compound is essential for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

This versatile chemical intermediate serves as a critical scaffold in numerous sophisticated synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable halogen sites.
• Agrochemical Development: Intermediate in the creation of novel herbicides, fungicides, and insecticides.
• Material Science: Precursor for organic electronic materials, such as ligands for OLEDs or catalysts.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Group Transformation: Serves as a starting point for further functionalization to create diverse chemical libraries.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine, 6-Chloro-8-Iodo-
CAS No.	1033463-28-3
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	6-Chloro-8-iodoimidazo[1,2-a]pyridine; 8-Iodo-6-chloroimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-chloro-8-iodo-; 1033463-28-3; 6-Chloro-8-iodo-imidazo[1,2-a]pyridine; AI3-34175; SCHEMBL2180625; ZINC000004069756.
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine, 6-Chloro-8-Iodo- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.