Description

2-Fluoro-4-(4-Methylsulfonylphenyl)Phenol is a high-value fluorinated phenolic intermediate with a methylsulfonylphenyl substituent, offering unique electronic and steric properties. This compound is critical for the synthesis of advanced pharmaceutical ingredients and agrochemicals, where its structure enables precise modulation of biological activity and material properties. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where the phenol and sulfone groups contribute to molecular alignment and charge transport properties.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce fluorine and polar sulfone groups into polymer backbones, improving chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed in Suzuki-Miyaura and other cross-coupling reactions as a versatile aryl halide/phenol coupling partner.
• Chemical Research & Development: A valuable tool compound for medicinal chemistry and material science research programs exploring structure-activity relationships.

Basic Information

Product Name	2-Fluoro-4-(4-Methylsulfonylphenyl)Phenol
CAS No.	1032825-01-6
Molecular Formula	C13H11FO3S
Molecular Weight	266.29 g/mol
Synonyms	4-(4-Methylsulfonylphenyl)-2-fluorophenol; 2-Fluoro-4-(4-(methylsulfonyl)phenyl)phenol; 2-Fluoro-4-[4-(methylsulfonyl)phenyl]phenol; Phenol, 2-fluoro-4-[4-(methylsulfonyl)phenyl]-; 1032825-01-6; 4-(4-Methanesulfonylphenyl)-2-fluorophenol
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(4-Methylsulfonylphenyl)Phenol is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets the stringent requirements for advanced synthesis. A detailed Certificate of Analysis (COA) with batch-specific results from HPLC, NMR, and GC-MS is provided with each shipment to guarantee supply chain transparency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.