Description

Carbamic Acid, n-[1-[4-(5-Chloro-3-Phenyl-1,6-Naphthyridin-2-Yl)Phenyl]Cyclobutyl]-, 1,1-Dimethylethyl Ester is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new drug molecules, especially in oncology and central nervous system (CNS) therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used as a building block in multi-step synthesis protocols for complex target molecules.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a reference standard or starting material for scaling up synthetic routes from laboratory to pilot plant scale.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study enzyme inhibition or receptor binding.

Basic Information

Item	Detail
Product Name	Carbamic Acid, n-[1-[4-(5-Chloro-3-Phenyl-1,6-Naphthyridin-2-Yl)Phenyl]Cyclobutyl]-, 1,1-Dimethylethyl Ester
CAS No.	1032349-99-7
Molecular Formula	C31H28ClN3O2
Molecular Weight	510.03 g/mol
Synonyms	tert-Butyl N-[1-[4-(5-chloro-3-phenyl-1,6-naphthyridin-2-yl)phenyl]cyclobutyl]carbamate; 1,1-Dimethylethyl N-[1-[4-(5-chloro-3-phenyl-1,6-naphthyridin-2-yl)phenyl]cyclobutyl]carbamate; BOC-protected naphthyridine intermediate; 1032349-99-7; Carbamic acid, N-[1-[4-(5-chloro-3-phenyl-1,6-naphthyridin-2-yl)phenyl]cyclobutyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[1-[4-(5-Chloro-3-Phenyl-1,6-Naphthyridin-2-Yl)Phenyl]Cyclobutyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided and available upon request. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.