Description

tert-Butyl 2'-Oxo-2',3'-Dihydro-1'H-Spiro[Piperidine-4,4'-Quinoline]-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic quinoline-piperidine scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas. Research and development teams in the global pharmaceutical and biotechnology sectors require this intermediate for its precise structural framework, which enables efficient lead optimization and the exploration of new chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) with potential neurological activity.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies due to its complex, privileged spirocyclic structure.
• Drug Discovery Programs: Serves as a core scaffold in the development of potential therapeutics for CNS disorders, such as antidepressants or anxiolytics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client drug discovery projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item	Detail
Product Name	tert-Butyl 2'-Oxo-2',3'-Dihydro-1'H-Spiro[Piperidine-4,4'-Quinoline]-1-Carboxylate
CAS No.	1032143-13-7
Molecular Formula	C18H24N2O3
Molecular Weight	316.40 g/mol
Synonyms	1-Boc-2',3'-dihydro-1'H-spiro[piperidine-4,4'-quinoline]-2'-one; 1-(tert-Butoxycarbonyl)-2',3'-dihydro-1'H-spiro[piperidine-4,4'-quinoline]-2'-one; tert-Butyl 2-oxo-1,3-dihydrospiro[quinoline-4,4'-piperidine]-1'-carboxylate; Spiro[piperidine-4,4'-quinoline]-1-carboxylic acid, 2',3'-dihydro-2'-oxo-, 1,1-dimethylethyl ester; 1032143-13-7; Boc-protected spiroquinolinone piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2'-Oxo-2',3'-Dihydro-1'H-Spiro[Piperidine-4,4'-Quinoline]-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices and can provide material tailored to specific project requirements, with documentation available for regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.