Description

E-8-Bromo-2-Chloro-7-Methoxy-3-(2-Nitro)Vinylquinoline is a high-purity, multi-functional quinoline derivative serving as a critical advanced pharmaceutical intermediate and synthetic building block. Its complex halogenated and nitrovinyl-substituted structure makes it invaluable for constructing novel molecular frameworks in medicinal chemistry. This compound is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in anti-infective, anti-cancer, and CNS-targeted therapeutic research.
• Agrochemical Research: Used as a building block for developing new pesticides, herbicides, and fungicides with enhanced efficacy.
• Organic Synthesis & Material Science: Serves as a versatile synthon for creating complex heterocyclic compounds and functional organic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	E-8-Bromo-2-Chloro-7-Methoxy-3-(2-Nitro)Vinylquinoline
CAS No.	1031929-46-0
Molecular Formula	C₁₂H₈BrClN₂O₃
Molecular Weight	343.56 g/mol
Synonyms	8-Bromo-2-chloro-7-methoxy-3-[(E)-2-nitroethenyl]quinoline; (E)-8-Bromo-2-chloro-7-methoxy-3-(2-nitrovinyl)quinoline; 3-[(E)-2-Nitroethenyl]-8-bromo-2-chloro-7-methoxyquinoline; Quinoline, 8-bromo-2-chloro-7-methoxy-3-[(E)-2-nitroethenyl]-; 1031929-46-0; E-8-Br-2-Cl-7-MeO-3-(NO2-Vinyl)quinoline
EINECS	Contact for details

Quality Control

Every batch of E-8-Bromo-2-Chloro-7-Methoxy-3-(2-Nitro)Vinylquinoline is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes data from HPLC, NMR, and MS. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.