Description

E-2,5-Dichloro-8-Methyl-3-(2-Nitro)Vinylquinoline is a specialized, high-value quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, featuring a nitrovinyl group on the quinoline core, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Building block for developing new generations of fungicides, herbicides, and plant growth regulators with enhanced efficacy.
• Material Science: Used in the research and development of organic semiconductors, light-emitting diodes (OLEDs), and other advanced functional materials due to its electron-accepting nitrovinyl moiety.
• Chemical Synthesis: Serves as a versatile dienophile in Diels-Alder reactions and a Michael acceptor in nucleophilic addition reactions for constructing complex molecular frameworks.
• Dye & Pigment Industry: Intermediate for synthesizing specialized quinoline dyes and colorants with specific light-fastness and chromatic properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	E-2,5-Dichloro-8-Methyl-3-(2-Nitro)Vinylquinoline
CAS No.	1031929-43-7
Molecular Formula	C₁₂H₈Cl₂N₂O₂
Molecular Weight	283.11 g/mol
Synonyms	(E)-2,5-Dichloro-8-methyl-3-[(2-nitroviny)]quinoline; 2,5-Dichloro-8-methyl-3-[(E)-2-nitroethenyl]quinoline; 3-[(E)-2-Nitroethenyl]-2,5-dichloro-8-methylquinoline; Quinoline, 2,5-dichloro-8-methyl-3-[(E)-2-nitroethenyl]-; 1031929-43-7; E-Isomer of Nitrovinylquinoline derivative
EINECS	Contact for details

Quality Control

Every batch of E-2,5-Dichloro-8-Methyl-3-(2-Nitro)Vinylquinoline is manufactured under strict quality management protocols. We guarantee high chemical purity and isomeric integrity, supported by comprehensive analytical characterization including HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0% (Area %)
E-Isomer Content (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.