Description

1-Methylindazole-6-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in kinase inhibitor and receptor modulator research.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and biochemical tools.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-Methylindazole-6-Carboxylic Acid
CAS No.	1031417-77-2
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	1-Methyl-1H-indazole-6-carboxylic acid; 6-Carboxy-1-methylindazole; 1-Methyl-6-indazolecarboxylic Acid; 1-Methyl-1H-indazole-6-carboxylate; 1031417-77-2; 1-Methylindazole-6-COOH; 6-(Methoxycarbonyl)-1-methylindazole (methyl ester form); 1-Methyl-6-indazole carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Methylindazole-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with customer-specific requirements and general industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.