Description

(1R,2R)-trans-1,2-Cyclopentanediamine Dihydrochloride is a high-purity chiral diamine salt, serving as a critical building block in asymmetric synthesis and pharmaceutical development. Its value lies in providing a rigid, stereodefined scaffold that is essential for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs), ligands, and catalysts.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand: Used to prepare chiral ligands for transition metal catalysts in enantioselective hydrogenation and cross-coupling reactions.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Resolution Agent: Functions as a chiral resolving agent for the separation of racemic mixtures of carboxylic acids and other compounds.
• Polymer Modification: Incorporated into specialty polymers to impart chirality and modify material properties for advanced applications.
• Academic & Process R&D: A valuable reagent for methodological studies in organic chemistry and scale-up process development.

Basic Information

Product Name	(1R,2R)-trans-1,2-Cyclopentanediamine Dihydrochloride
CAS No.	1030390-38-5
Molecular Formula	C5H14N2·2HCl
Molecular Weight	191.10 g/mol
Synonyms	(1R,2R)-(-)-1,2-Diaminocyclopentane Dihydrochloride; (1R,2R)-trans-1,2-Diaminocyclopentane Dihydrochloride; (1R,2R)-1,2-Cyclopentanediamine Dihydrochloride; (1R,2R)-DACH·2HCl; trans-(1R,2R)-1,2-Cyclopentanediamine Dihydrochloride; (1R,2R)-Cyclopentane-1,2-diamine Dihydrochloride; (1R,2R)-1,2-Diaminocyclopentane Hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our (1R,2R)-trans-1,2-Cyclopentanediamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity compliant with research and cGMP starting material standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.