Description

4(1H)-Quinolinone, 5,6-Difluoro-2,3-Dihydro- is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly within medicinal chemistry programs targeting novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its fused quinolinone structure with fluorine substitutions.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides and pesticides, where the difluoro motif can enhance biological activity and stability.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and advanced polymers where fluorinated aromatic systems are required.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for biochemical assays.

Basic Information

Product Name	4(1H)-Quinolinone, 5,6-Difluoro-2,3-Dihydro-
CAS No.	1029721-35-4
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	5,6-Difluoro-2,3-dihydro-4(1H)-quinolinone; 5,6-Difluoro-1,2,3,4-tetrahydro-4-oxoquinoline; 5,6-Difluoro-1,2,3,4-tetrahydroquinolin-4-one; 5,6-Difluoro-3,4-dihydro-2H-quinolin-4-one; 5,6-Difluoro-3,4-dihydroquinolin-4(1H)-one; 5,6-Difluoro-1,4-dihydroquinolin-4-one; 5,6-Difluoro-4-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinolinone, 5,6-Difluoro-2,3-Dihydro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard grade meets typical research and development requirements, with custom purity grades available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.