Description

5-Chloro-1,2,3,4-tetrahydro-2,6-naphthyridine is a high-value, heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its unique fused-ring structure containing nitrogen and chlorine makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to develop molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific naphthyridine core.

Basic Information

Product Name	5-Chloro-1,2,3,4-tetrahydro-2,6-naphthyridine
CAS No.	1029720-16-8
Molecular Formula	C8H9ClN2
Molecular Weight	168.62 g/mol
Synonyms	5-Chloro-1,2,3,4-tetrahydro-2,6-naphthyridine; 5-Chloro-2,3,4,5-tetrahydro-1H-2,6-naphthyridine; 2,6-Naphthyridine, 5-chloro-1,2,3,4-tetrahydro-; 5-Chloro-1,2,3,4-tetrahydro-2,6-naphthyridine; 1029720-16-8; 5-Chloro-1,2,3,4-tetrahydro-2,6-naphthyridine (CAS 1029720-16-8)
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,2,3,4-tetrahydro-2,6-naphthyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.