Description

7'-Methyl-2',3',4',6'-Tetrahydrospiro[Cyclohexane-1,1'-Pyrazolo[3,4-B]Pyridine]-3'-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and heterocyclic architecture. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly those targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique spirocyclic scaffold.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries for high-throughput screening in drug discovery.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	7'-Methyl-2',3',4',6'-Tetrahydrospiro[Cyclohexane-1,1'-Pyrazolo[3,4-B]Pyridine]-3'-One
CAS No.	1029475-77-1
Molecular Formula	C₁₂H₁₇N₃O
Molecular Weight	219.28 g/mol
Synonyms	7'-Methyl-2',3',4',6'-tetrahydrospiro[cyclohexane-1,1'-pyrazolo[3,4-b]pyridin]-3'-one; 7'-Methyl-2',3',4',6'-tetrahydro-1'H-spiro[cyclohexane-1,5'-pyrazolo[3,4-b]pyridin]-3'-one; Spiro[cyclohexane-1,1'-pyrazolo[3,4-b]pyridine]-3'-one, 2',3',4',6'-tetrahydro-7'-methyl-; 1029475-77-1
EINECS	Contact for details

Quality Control

Our production of 7'-Methyl-2',3',4',6'-Tetrahydrospiro[Cyclohexane-1,1'-Pyrazolo[3,4-B]Pyridine]-3'-One adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures a reliable supply of this high-value intermediate for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.