Description

1-(3-Aminopyridin-2-Yl)Azetidin-3-Ol is a versatile heterocyclic building block featuring both an amino and a hydroxyl functional group. This compound is of significant value in pharmaceutical research and development, particularly as a key intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Development: Utilized in organometallic chemistry for the preparation of novel ligands and catalysts.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.
• Academic Research: Employed in university and institutional labs for methodological studies and novel heterocycle chemistry.

Basic Information

Product Name	1-(3-Aminopyridin-2-Yl)Azetidin-3-Ol
CAS No.	1029432-79-8
Molecular Formula	C8H11N3O
Molecular Weight	165.19 g/mol
Synonyms	3-Azetidinol, 1-(3-amino-2-pyridinyl)-; 1-(3-Aminopyridin-2-yl)azetidin-3-ol; 2-(3-Hydroxyazetidin-1-yl)pyridin-3-amine; 3-Amino-2-(3-hydroxyazetidin-1-yl)pyridine; Azetidin-3-ol, 1-(3-amino-2-pyridinyl)-; 1-(3-Amino-2-pyridyl)azetidin-3-ol
EINECS	Contact for details

Quality Control

Our 1-(3-Aminopyridin-2-Yl)Azetidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.