Description

2,4-Dichloro-7,8-Dihydro-6H-Quinolin-5-One is a high-purity, advanced pharmaceutical intermediate characterized by its fused quinoline core structure. This compound is of significant commercial importance as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a key scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic compounds due to its reactive dichloro and ketone functional groups.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and organic electronic materials.
• Biochemical Research: Employed in the study of enzyme inhibitors and the development of molecular probes.

Basic Information

Product Name	2,4-Dichloro-7,8-Dihydro-6H-Quinolin-5-One
CAS No.	1028330-50-8
Molecular Formula	C9H5Cl2NO
Molecular Weight	214.05 g/mol
Synonyms	2,4-Dichloro-5-oxo-7,8-dihydro-6H-quinoline; 5(6H)-Quinolinone, 2,4-dichloro-7,8-dihydro-; 2,4-Dichloro-5,6,7,8-tetrahydroquinolin-5-one; 2,4-Dichloro-7,8-dihydroquinolin-5(6H)-one; 1028330-50-8; DHQ derivative; Dihydroquinolinone intermediate
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7,8-Dihydro-6H-Quinolin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.