Description

tert-Butyl 2,2,3,3-Tetramethyl-4-Oxo-3,4-Dihydroquinoline-1(2H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique dihydroquinoline core structure. This compound is of significant commercial value for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Reagent: Serves as a protected amine precursor or a complex scaffold for further functionalization in multi-step synthetic routes.
• Material Science Precursor: Potential use in the development of organic electronic materials or functional dyes due to its conjugated system.
• Academic & Contract Research: Essential for medicinal chemistry programs and process chemistry optimization in R&D laboratories.

Basic Information

Product Name	tert-Butyl 2,2,3,3-Tetramethyl-4-Oxo-3,4-Dihydroquinoline-1(2H)-Carboxylate
CAS No.	1028304-66-6
Molecular Formula	C₁₈H₂₅NO₃
Molecular Weight	303.40 g/mol
Synonyms	1,2-Dihydro-4-oxo-2,2,3,3-tetramethylquinoline-1-carboxylic acid tert-butyl ester; tert-Butyl 2,2,3,3-tetramethyl-4-oxo-1,2,3,4-tetrahydroquinoline-1-carboxylate; 1-Boc-2,2,3,3-tetramethyl-1,2,3,4-tetrahydro-4-oxoquinoline; 1-N-Boc-2,2,3,3-tetramethyl-1,2,3,4-tetrahydroquinolin-4-one; 1028304-66-6; BOC-protected tetramethyl dihydroquinolinone.
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,2,3,3-Tetramethyl-4-Oxo-3,4-Dihydroquinoline-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.