Description

Diethyl 2-(4-Chlorobenzamido)-2-[(2-Oxo-1,2-Dihydroquinolin-4-Yl)Methyl]Malonate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing novel heterocyclic frameworks. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as oncology and inflammation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Diethyl 2-(4-Chlorobenzamido)-2-[(2-Oxo-1,2-Dihydroquinolin-4-Yl)Methyl]Malonate
CAS No.	1028268-32-7
Molecular Formula	C24H23ClN2O6
Molecular Weight	470.90 g/mol
Synonyms	Diethyl (4-chlorobenzamido)((2-oxo-1,2-dihydroquinolin-4-yl)methyl)malonate; 4-Chloro-N-[(2-oxo-1,2-dihydro-4-quinolinyl)methyl]-N-(1,3-dicarbethoxy-2-propylidene)benzamide; 1028268-32-7; 2-(4-Chlorobenzamido)-2-[(2-oxo-1,2-dihydroquinolin-4-yl)methyl]malonic Acid Diethyl Ester; Malonic acid, 2-(4-chlorobenzamido)-2-[(2-oxo-1,2-dihydro-4-quinolinyl)methyl]-, diethyl ester; Diethyl 2-(4-chlorobenzamido)-2-[(2-oxo-1H-quinolin-4-yl)methyl]malonate
EINECS	Contact for details

Quality Control

Our Diethyl 2-(4-Chlorobenzamido)-2-[(2-Oxo-1,2-Dihydroquinolin-4-Yl)Methyl]Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.