Description

7-Fluoro-8-Nitroquinazolin-4-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinazolinone core functionalized with fluoro and nitro groups. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel drug candidates. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities for oncology and other therapeutic areas.
• Process Development: Serves as a starting material or intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	7-Fluoro-8-Nitroquinazolin-4-Ol
CAS No.	1027929-81-2
Molecular Formula	C8H4FN3O3
Molecular Weight	209.14 g/mol
Synonyms	7-Fluoro-8-nitro-4-quinazolinol; 7-Fluoro-8-nitroquinazolin-4(3H)-one; 4-Hydroxy-7-fluoro-8-nitroquinazoline; 8-Nitro-7-fluoro-4(3H)-quinazolinone; 7-Fluoro-8-nitro-4(3H)-quinazolinone; 7-Fluoro-8-nitro-4-hydroxyquinazoline; 1027929-81-2
EINECS	Contact for details

Quality Control

Our 7-Fluoro-8-Nitroquinazolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere when appropriate for long-term storage.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.