Description

2-Methoxy-4-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a methoxy group with a trifluoromethyl substituent on the phenol ring, provides valuable electronic and steric properties for modifying molecular characteristics. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group contributes to improved biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Acts as a functional monomer or additive to introduce fluorine into polymer chains, enhancing material properties like chemical resistance and thermal stability.
• Organic Electronics: Employed in the synthesis of charge-transport materials and emitters for organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Methoxy-4-(Trifluoromethyl)Phenol
CAS No.	1027888-79-4
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	4-(Trifluoromethyl)-2-methoxyphenol; 2-Methoxy-4-(trifluoromethyl)phenol; 4-Trifluoromethylguaiacol; 2-Methoxy-alpha,alpha,α-trifluoro-p-cresol; Guaiacol, 4-trifluoromethyl-; p-(Trifluoromethyl)guaiacol; 1-Hydroxy-2-methoxy-4-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our production of 2-Methoxy-4-(Trifluoromethyl)Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with every shipment. We support custom synthesis and can tailor purity specifications to meet specific research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.