Description

3-Hydroxy-1,2:5,6-Dibenzocyclooct-7-Yne is a high-purity, advanced organic intermediate featuring a unique strained cyclic alkyne structure fused with aromatic rings. This compound is of significant value in pharmaceutical research and materials science due to its potential as a versatile building block for click chemistry and the synthesis of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring rigid, three-dimensional scaffolds.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer functionalization, and material surface modification.
• Ligand Synthesis: Acts as a starting material for developing novel chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in creating new active ingredients with potential insecticidal or herbicidal properties.
• Advanced Material Development: Used in the design of organic semiconductors, liquid crystals, or polymers with specific optical or electronic properties.
• Academic & Institutional Research: A valuable tool for studying strained alkynes, reaction mechanisms, and developing new synthetic methodologies.

Basic Information

Product Name	3-Hydroxy-1,2:5,6-Dibenzocyclooct-7-Yne
CAS No.	1027338-06-2
Molecular Formula	C16H12O
Molecular Weight	220.27 g/mol
Synonyms	3-Hydroxydibenzocyclooctyne; 3-Hydroxy-DIBO; 3-OH-DIBO; 1,2:5,6-Dibenzocyclooct-7-yn-3-ol; Dibenzocyclooctynol; DBCO alcohol derivative; Bicyclo[6.2.0]deca-1,3,5,7,9-pentaen-4-ol (related structure); Strain-promoted alkyne reagent precursor
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxy-1,2:5,6-Dibenzocyclooct-7-Yne is manufactured and tested under strict quality management systems to ensure consistency and reliability for research and development. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent purity standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.