Description

1-(Aminomethyl)Cyclopropane-1-Carboxamide is a versatile and high-value cyclopropane-based building block with a bifunctional amine and amide group. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures with constrained geometry. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring can impart metabolic stability and unique biological activity.
• Peptidomimetics & Bioisosteres: The constrained structure serves as a valuable scaffold in designing peptide mimics and bioisosteric replacements to improve drug-like properties.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-(Aminomethyl)Cyclopropane-1-Carboxamide
CAS No.	1027337-85-4
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	Cyclopropanecarboxamide, 1-(aminomethyl)-; 1-(Aminomethyl)cyclopropanecarboxamide; 1-Carbamoylcyclopropylmethylamine; Aminomethylcyclopropanecarboxamide; (1-Aminomethylcyclopropyl)carboxamide; 1-(Aminomethyl)-1-cyclopropanecarboxamide; Cyclopropane-1-carboxamide, 1-(aminomethyl)-; 1-Cyclopropanecarboxamide, 1-(aminomethyl)-
EINECS	Contact for details

Quality Control

Our 1-(Aminomethyl)Cyclopropane-1-Carboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.