Description

6-((tert-Butoxycarbonyl)Amino)Quinoline-2-Carboxylic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, specifically for the synthesis of quinoline-based active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly those containing the quinoline pharmacophore.
• Peptidomimetic Research: Used to incorporate quinoline-2-carboxylic acid motifs into peptide backbones, creating analogs with enhanced stability or biological activity.
• Ligand Synthesis for Catalysis: Serves as a starting material for preparing sophisticated nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The quinoline core can be utilized to build fluorescent tags and molecular sensors for biochemical and diagnostic applications.
• Agrochemical Synthesis: Acts as an intermediate in the development of new agrochemicals, such as herbicides and fungicides, that leverage the biological activity of quinoline derivatives.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	6-((tert-Butoxycarbonyl)Amino)Quinoline-2-Carboxylic Acid
CAS No.	1023816-81-0
Molecular Formula	C15H16N2O4
Molecular Weight	288.30 g/mol
Synonyms	2-Quinolinecarboxylic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-; 6-((Boc)Amino)quinoline-2-carboxylic acid; 6-(N-Boc-amino)quinoline-2-carboxylic acid; Boc-6-AQCA; tert-Butyl (6-(carboxy)quinolin-2-yl)carbamate; 6-(tert-Butoxycarbonylamino)quinoline-2-carboxylic acid; 6-Boc-amino-2-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-((tert-Butoxycarbonyl)Amino)Quinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.