Description

(R)-2-Methyl-4-Nitrobutan-1-Ol is a high-value chiral building block and intermediate of significant importance in asymmetric synthesis. Its unique structure, featuring both a nitro group and a chiral center, makes it a versatile precursor for the production of pharmaceuticals, agrochemicals, and fine chemicals. This compound is particularly sought after by research institutions and industrial manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various APIs, including potential candidates for cardiovascular, neurological, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where stereochemistry is critical for biological activity.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and other specialty chemicals requiring high enantiomeric purity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research to develop new catalytic methodologies.
• Material Science: Potential intermediate for the synthesis of chiral polymers or liquid crystals with specific optical properties.

Basic Information

Product Name	(R)-2-Methyl-4-Nitrobutan-1-Ol
CAS No.	1022985-41-6
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(R)-2-Methyl-4-nitro-1-butanol; (R)-4-Nitro-2-methylbutan-1-ol; (2R)-2-Methyl-4-nitrobutan-1-ol; (R)-1-Hydroxy-2-methyl-4-nitrobutane; 4-Nitro-2-methyl-1-butanol, (R)-; (R)-2-Methyl-4-nitrobutanol; (R)-HMN; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure the highest standards of purity and consistency for our chiral intermediates. Every batch of (R)-2-Methyl-4-Nitrobutan-1-Ol is characterized using advanced analytical techniques including HPLC, GC, and chiral analysis to confirm identity, assay, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.