Description

2-Bromo-5-Iodo-4-Methylbenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals developing new active ingredients, where precise structural control is paramount for achieving desired biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of both bromo and iodo substituents.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Bromo-5-Iodo-4-Methylbenzoic Acid
CAS No.	1022983-53-4
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	4-Methyl-2-bromo-5-iodobenzoic Acid; 2-Bromo-5-iodo-p-toluic Acid; Benzoic acid, 2-bromo-5-iodo-4-methyl-; 5-Iodo-2-bromo-4-methylbenzoic Acid; 2-Bromo-5-iodo-4-methyl-benzoic Acid; 4-Methyl-5-iodo-2-bromobenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Iodo-4-Methylbenzoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications for identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming the product meets the agreed-upon specifications for your application.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.