Description

3-Bromo-5-Iodo-2-Methyl Benzoic Acid is a high-purity, multi-halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where precise halogen placement is key to modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides with specific halogenated aromatic cores.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized polymers and liquid crystals with tailored electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions where applicable.

Basic Information

Product Name	3-Bromo-5-Iodo-2-Methyl Benzoic Acid
CAS No.	1022983-50-1
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	2-Methyl-3-bromo-5-iodobenzoic acid; 3-Bromo-5-iodo-2-methylbenzoic acid; Benzoic acid, 3-bromo-5-iodo-2-methyl-; 3-Br-5-I-2-Me-BA; 2-Methyl-3,5-dihalobenzoic acid (mixed halogen); 5-Iodo-3-bromo-o-toluic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Iodo-2-Methyl Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry and inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.