Description

2-Methylquinoline-6-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel quinoline-based molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in the development of kinase inhibitors, anti-malarial agents, and other bioactive quinoline derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides that require specific quinoline scaffolds.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Methylquinoline-6-Boronic Acid Pinacol Ester
CAS No.	1022090-86-3
Molecular Formula	C₁₇H₂₂BNO₂
Molecular Weight	283.18 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylquinoline; 2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; 2-Methylquinolin-6-ylboronic acid pinacol ester; 2-Methyl-6-quinolineboronic acid pinacol ester; 2-Me-6-Quin-BPin; Quinoline-6-boronic acid pinacol ester, 2-methyl-; B-(2-Methyl-6-quinolyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methylquinoline-6-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.