Description

(E)-3-[2-(7-Chloro-2-Quinolinyl)Ethenyl]Benzoyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a key building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for their critical synthesis pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammatory pathways or acting as leukotriene receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the quinoline and benzoyl chloride functionalities are key structural motifs.
• Fine Chemical Production: Serves as a specialized building block for creating complex dyes, pigments, and functional materials with specific optical or electronic properties.
• Research & Development: An important reagent in academic and industrial R&D labs for exploring new organic reactions and synthesizing libraries of compounds for biological screening.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes due to its reactive acyl chloride group.

Basic Information

Item	Details
Product Name	(E)-3-[2-(7-Chloro-2-Quinolinyl)Ethenyl]Benzoyl Chloride
CAS No.	1021946-05-3
Molecular Formula	C18H11Cl2NO
Molecular Weight	328.19 g/mol
Synonyms	(E)-3-[2-(7-Chloro-2-quinolyl)vinyl]benzoyl chloride; 3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]benzoyl chloride; (E)-3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-benzoyl chloride; 7-Chloro-2-[(E)-2-(3-chlorocarbonylphenyl)ethenyl]quinoline; MFCD11871103; Benzoyl chloride, 3-[2-(7-chloro-2-quinolinyl)ethenyl]-, (E)-; (E)-3-(2-(7-Chloroquinolin-2-yl)vinyl)benzoyl chloride
EINECS	Contact for details

Quality Control

Our (E)-3-[2-(7-Chloro-2-Quinolinyl)Ethenyl]Benzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods (IR, NMR), and levels of key impurities. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.