Description

7-Chloro-4-Hydroxy-6-Iodo-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated structure makes it indispensable for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in anti-malarial, anti-cancer, and anti-inflammatory research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinoline core.
• Organic Synthesis Reagent: Serves as a versatile precursor for creating more complex heterocyclic compounds and fine chemicals.
• Material Science: Investigated for use in the synthesis of organic semiconductors, ligands for catalysis, and fluorescent dyes.
• Academic & R&D: Essential for methodological studies and discovery chemistry in university and industrial laboratories.

Basic Information

Product Name	7-Chloro-4-Hydroxy-6-Iodo-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1021913-01-8
Molecular Formula	C₁₃H₉ClINO₃
Molecular Weight	389.57 g/mol
Synonyms	Ethyl 7-Chloro-4-hydroxy-6-iodoquinoline-3-carboxylate; 7-Chloro-4-hydroxy-6-iodo-3-quinolinecarboxylic Acid Ethyl Ester; 4-Hydroxy-7-chloro-6-iodoquinoline-3-carboxylic Acid Ethyl Ester; 1021913-01-8; AI3-63562; SCHEMBL2180625; ZINC000095909996; Ethyl 7-chloro-4-oxo-6-iodo-1,4-dihydroquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Hydroxy-6-Iodo-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (from research to GMP) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.