Description

2,5-(Dimethoxy-D6)-4-Bromoamphetamine is a deuterated analog of a substituted amphetamine, featuring deuterium atoms at the methoxy positions. This compound is of significant value in pharmaceutical and forensic research, particularly for use as an internal standard in mass spectrometry and other analytical techniques. It is primarily utilized by analytical laboratories, forensic science departments, and pharmaceutical R&D teams engaged in method development, metabolism studies, and substance identification.

Application

• Analytical Reference Standard: Serves as a critical internal standard for the precise quantification of related amphetamine compounds in complex matrices using LC-MS/MS and GC-MS.
• Forensic Toxicology: Employed in the development and validation of analytical methods for the detection and confirmation of controlled substances in biological samples.
• Metabolite Studies: Used in pharmaceutical research to trace and identify metabolites in pharmacokinetic and metabolic pathway investigations.
• Method Development & Validation: Provides a stable, isotopically-labeled benchmark for ensuring accuracy, precision, and reliability in new analytical procedures.
• Quality Control (QC) Testing: Acts as a calibrant or system suitability check in high-purity analytical workflows within QC laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Essential for achieving high-accuracy quantitative results by correcting for sample preparation and instrument variability.

Basic Information

Product Name	2,5-(Dimethoxy-D6)-4-Bromoamphetamine
CAS No.	1021684-64-9
Molecular Formula	C11H9D6BrNO2
Molecular Weight	287.20 g/mol (approx.)
Synonyms	4-Bromo-2,5-bis(methoxy-d3)amphetamine; 4-Bromo-2,5-dimethoxy-D6-amphetamine; 1-(4-Bromo-2,5-dimethoxyphenyl)propan-2-amine-D6; DOB-D6 (deuterated analog); 2,5-Dimethoxy-4-bromoamphetamine-D6; 4-Bromo-2,5-dimethoxyamphetamine hexadeuterated; 2,5-(Dimethoxy-D6)-4-bromo-α-methylphenethylamine
EINECS	Contact for details

Quality Control

Our 2,5-(Dimethoxy-D6)-4-Bromoamphetamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic purity (D-enrichment), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect the material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.