Description

3-(1,7-Dimethyl-2-Oxo-1,2-Dihydro-1,6-Naphthyridin-3-Yl)-4-Methylbenzoic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and targeted drug discovery. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies due to its specific naphthyridine-based scaffold.
• Chemical Biology: Serves as a probe or precursor in studying enzyme function and biological pathways.
• Process Chemistry: Employed in route scouting and scale-up studies for new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and publications.
• Custom Synthesis: Starting material for the contract manufacturing of proprietary compounds for biotech clients.

Basic Information

Product Name	3-(1,7-Dimethyl-2-Oxo-1,2-Dihydro-1,6-Naphthyridin-3-Yl)-4-Methylbenzoic Acid
CAS No.	1021535-38-5
Molecular Formula	C18H16N2O3
Molecular Weight	308.33 g/mol
Synonyms	4-Methyl-3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)benzoic acid; 3-(1,7-Dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-4-methylbenzoic acid; 1,6-Naphthyridine-3-carboxylic acid derivative; Benzoic acid, 4-methyl-3-(1,7-dimethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-; 1021535-38-5; 3-(1,7-Dimethyl-2-oxo-1,6-dihydronaphthyridin-3-yl)-4-methylbenzoic acid
EINECS	Contact for details

Quality Control

Our 3-(1,7-Dimethyl-2-Oxo-1,2-Dihydro-1,6-Naphthyridin-3-Yl)-4-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under these conditions but should be handled with care in accordance with standard laboratory safety procedures for fine chemicals.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.