Description

3-(5-Amino-2-Methylphenyl)-1,7-Dimethyl-1,6-Naphthyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, especially for creating targeted small-molecule therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for drug discovery programs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a versatile precursor for constructing complex naphthyridine-based heterocyclic compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	3-(5-Amino-2-Methylphenyl)-1,7-Dimethyl-1,6-Naphthyridin-2(1H)-One
CAS No.	1021535-31-8
Molecular Formula	C₁₇H₁₇N₃O
Molecular Weight	279.34 g/mol
Synonyms	1,7-Dimethyl-3-(5-amino-2-methylphenyl)-1,6-naphthyridin-2(1H)-one; 3-(5-Amino-2-methylphenyl)-1,7-dimethyl-1,6-naphthyridin-2-ol; 1021535-31-8; Amino-methylphenyl dimethyl naphthyridinone; Naphthyridinone derivative intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-(5-Amino-2-Methylphenyl)-1,7-Dimethyl-1,6-Naphthyridin-2(1H)-One is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.