Description

2-((Tetrahydro-2H-Pyran-2-Yl)Methox Y)Benzoic Acid is a specialized organic compound featuring a benzoic acid core protected by a tetrahydropyranyl (THP) ether group. This structural motif makes it a valuable protected intermediate in multi-step synthetic routes, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by process chemists and R&D laboratories engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, where the THP group acts as a protecting group for the phenolic hydroxyl during subsequent reactions.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel chemical entities, leveraging its reactivity for further functionalization.
• Agrochemical Development: Employed as a precursor in the synthesis of advanced herbicides, fungicides, or plant growth regulators.
• Material Science: Potential use in the synthesis of monomers or additives for specialized polymers and advanced materials.
• Chemical Biology: Can be utilized in probe or linker synthesis for studying biological systems and pathways.

Basic Information

Product Name	2-((Tetrahydro-2H-Pyran-2-Yl)Methox Y)Benzoic Acid
CAS No.	1021144-50-2
Molecular Formula	C₁₃H₁₆O₄
Molecular Weight	236.26 g/mol
Synonyms	2-(Tetrahydro-2H-pyran-2-ylmethoxy)benzoic acid; Benzoic acid, 2-[(tetrahydro-2H-pyran-2-yl)methoxy]-; 2-(THP-O-Methoxy)benzoic Acid; 2-(Tetrahydropyran-2-ylmethoxy)benzoic acid; 2-[(Oxan-2-yl)methoxy]benzoic acid; THP-protected Salicylic Acid Derivative; CAS 1021144-50-2
EINECS	Contact for details

Quality Control

Our 2-((Tetrahydro-2H-Pyran-2-Yl)Methox Y)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.