Description

4-((Tetrahydro-2H-Pyran-2-Yl)Methox Y)Benzoic Acid CAS NO 1020999-22-7 is a protected benzoic acid derivative, where the phenolic hydroxyl group is masked with a tetrahydropyranyl (THP) ether protecting group. This compound is a crucial pharmaceutical intermediate and organic synthesis building block, enabling the selective manipulation of molecular structures in complex synthetic pathways. It is primarily required by R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used as a protected benzoic acid precursor in peptide coupling, esterification, and amidation reactions.
• Agrochemical Synthesis: Intermediate in the development of herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Research: Serves as a starting material or intermediate for synthesizing advanced organic electronic materials.
• Polymer Chemistry: Monomer or modifier for creating specialty polymers with specific functional properties.
• Academic & Industrial R&D: Essential for method development and exploratory chemistry in medicinal and synthetic chemistry programs.

Basic Information

Product Name	4-((Tetrahydro-2H-Pyran-2-Yl)Methox Y)Benzoic Acid
CAS No.	1020999-22-7
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	4-(Tetrahydro-2H-pyran-2-ylmethoxy)benzoic acid; 4-[(Tetrahydro-2H-pyran-2-yl)oxy]benzoic acid; Benzoic acid, 4-((tetrahydro-2H-pyran-2-yl)oxy)-; 4-(THP-O)Benzoic Acid; 4-(Tetrahydropyran-2-yloxymethyl)benzoic acid; 4-(2-Tetrahydropyranyloxymethyl)benzoic acid; THP-protected 4-hydroxybenzoic acid
EINECS	Contact for details

Quality Control

Our 4-((Tetrahydro-2H-Pyran-2-Yl)Methox Y)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.