Description

2-Bromo-3,4,5-Trifluoronitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoro and bromo substitution pattern makes it an exceptionally valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling the rapid diversification of chemical space.
• Fluorine Chemistry Exploration: A valuable reagent for studying nucleophilic aromatic substitution (SNAr) and other reactions specific to polyfluorinated arenes.

Basic Information

Product Name	2-Bromo-3,4,5-Trifluoronitrobenzene
CAS No.	1020718-01-7
Molecular Formula	C6HBrF3NO2
Molecular Weight	257.98 g/mol
Synonyms	1-Bromo-2,3,4-trifluoro-5-nitrobenzene; 2,3,4-Trifluoro-1-bromo-5-nitrobenzene; Benzene, 1-bromo-2,3,4-trifluoro-5-nitro-; 2-Bromo-3,4,5-trifluoronitrobenzene; 3,4,5-Trifluoro-2-bromonitrobenzene; 5-Bromo-2,3,4-trifluoronitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,4,5-Trifluoronitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring material of high purity and reliable traceability for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.