Description

Ethyl 6-Bromoquinoline-2-Carboxylate is a high-purity, versatile brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive bromine substituent and ester functionality, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in the development of kinase inhibitors, antimicrobial agents, and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the creation of new pesticides, herbicides, and fungicides, leveraging the quinoline scaffold's bioactivity.
• Material Science Precursor: Serves as a starting material for the synthesis of organic ligands, dyes, and functional polymers with specific electronic or photophysical properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other metal-catalyzed transformations due to the presence of the bromine atom, facilitating carbon-carbon bond formation.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new reaction pathways in university and corporate research laboratories.

Basic Information

Product Name	Ethyl 6-Bromoquinoline-2-Carboxylate
CAS No.	1020572-61-5
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	6-Bromoquinoline-2-carboxylic acid ethyl ester; Ethyl 6-bromoquinoline-2-carboxylate; 2-Quinolinecarboxylic acid, 6-bromo-, ethyl ester; 6-Bromo-2-quinolinecarboxylic acid ethyl ester; Ethyl 6-bromo-2-quinolinecarboxylate; 6-Bromoquinaldine-2-carboxylic acid ethyl ester (non-standard); 6-Bromoquinoline-2-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromoquinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.