Description

8-Bromo-6-Trifluoromethoxyquinoline is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique halogenated and trifluoromethoxy-substituted quinoline structure makes it a critical precursor for developing novel bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex heterocyclic motifs into their molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new generation pesticides, herbicides, and fungicides due to the bioactivity-enhancing properties of the quinoline core and halogen substituents.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, organic semiconductors, and light-emitting materials.
• Chemical Biology & Probe Development: Employed in the design of fluorescent probes, enzyme inhibitors, and other molecular tools for biochemical and diagnostic applications.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct more complex polycyclic or functionalized molecular architectures.

Basic Information

Product Name	8-Bromo-6-Trifluoromethoxyquinoline
CAS No.	1020253-25-1
Molecular Formula	C₁₁H₅BrF₃NO
Molecular Weight	304.06 g/mol
Synonyms	8-Bromo-6-(trifluoromethoxy)quinoline; Quinoline, 8-bromo-6-(trifluoromethoxy)-; 6-Trifluoromethoxy-8-bromoquinoline; 8-Bromo-6-trifluoromethoxy-quinoline; 1020253-25-1
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC, NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.