Description

1-(2-Bromophenoxy)-4-Fluoro-2-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates bromo, fluoro, and nitro functional groups on a biphenyl ether scaffold, enabling precise structural modifications. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, where the halogen and nitro groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Nucleophilic Aromatic Substitution: The activated fluoro and nitro groups allow for selective displacement reactions to create diverse chemical libraries.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Item	Detail
Product Name	1-(2-Bromophenoxy)-4-Fluoro-2-Nitrobenzene
CAS No.	1019508-64-5
Molecular Formula	C12H7BrFNO3
Molecular Weight	312.10 g/mol
Synonyms	4-Fluoro-2-nitro-1-(2-bromophenoxy)benzene; 2-Bromo-1-(4-fluoro-2-nitrophenoxy)benzene; 1-(2-Bromophenoxy)-4-fluoro-2-nitrobenzene; 2-Bromophenyl 4-fluoro-2-nitrophenyl ether; (2-Bromophenoxy)(4-fluoro-2-nitrophenyl); Aromatic bromo-fluoro-nitro ether; Building block 1019508-64-5
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Bromophenoxy)-4-Fluoro-2-Nitrobenzene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency to meet the rigorous demands of research and process chemistry. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.