Description

5,8-Dichloro-1,2,3,4-Tetrahydroquinoline is a halogenated tetrahydroquinoline derivative, a versatile and valuable synthetic intermediate in advanced organic chemistry. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the unique 5,8-dichloro-tetrahydroquinoline scaffold into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the chlorinated tetrahydroquinoline structure can impart specific biological activity.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology & Proteomics: Employed as a scaffold for creating molecular probes and tool compounds to study biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including novel cross-coupling and cyclization reactions.

Basic Information

Product Name	5,8-Dichloro-1,2,3,4-Tetrahydroquinoline
CAS No.	1019385-18-2
Molecular Formula	C9H9Cl2N
Molecular Weight	202.08 g/mol
Synonyms	5,8-Dichloro-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-5,8-dichloroquinoline; 5,8-Dichlorotetrahydroquinoline; Quinoline, 5,8-dichloro-1,2,3,4-tetrahydro-; 1019385-18-2
EINECS	Contact for details

Quality Control

Our 5,8-Dichloro-1,2,3,4-Tetrahydroquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring reliable and consistent synthetic intermediates for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.