Description

4,5-Dichloro-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those with quinoline-based pharmacophores.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and insecticides where the quinoline scaffold provides biological activity.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, ester hydrolysis, and cyclization reactions to construct more complex heterocyclic systems.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4,5-Dichloro-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1019345-45-9
Molecular Formula	C₁₃H₁₁Cl₂NO₃
Molecular Weight	300.14 g/mol
Synonyms	Ethyl 4,5-dichloro-8-methoxyquinoline-3-carboxylate; 8-Methoxy-4,5-dichloroquinoline-3-carboxylic acid ethyl ester; 4,5-Dichloro-8-methoxy-3-quinolinecarboxylic acid ethyl ester; Quinoline-3-carboxylic acid, 4,5-dichloro-8-methoxy-, ethyl ester; 1019345-45-9; Ethyl 4,5-dichloro-8-methoxy-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-8-Methoxyquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.