Description

6-Fluoroh-Imidazo[1,2-A]Pyridin-3-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant interest in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and advanced fine chemical sectors seeking to incorporate its unique imidazopyridine scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its fluorinated imidazopyridine core.
• Process Chemistry & Scale-Up: Serves as a starting material or advanced intermediate in the development of scalable synthetic routes for potential APIs.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biological target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds for clients.

Basic Information

Product Name	6-Fluoroh-Imidazo[1,2-A]Pyridin-3-Carboxylic Acid
CAS No.	1019021-85-2
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	6-Fluoroimidazo[1,2-a]pyridine-3-carboxylic acid; 6-Fluoro-3-imidazo[1,2-a]pyridinecarboxylic acid; 6-Fluoro-1H-imidazo[1,2-a]pyridine-3-carboxylic acid; Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-fluoro-; 1019021-85-2; 6-Fluoroimidazo(1,2-a)pyridine-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 6-Fluoroh-Imidazo[1,2-A]Pyridin-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.