Description

6-Bromo-8-Fluoroquinolin-4-Ol is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated quinoline scaffold, which serves as a critical precursor for developing novel pharmacologically active compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in antimicrobial, anticancer, and CNS-active therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a building block for creating functionalized organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring specialized fluorinated and brominated quinoline chemistry.

Basic Information

Product Name	6-Bromo-8-Fluoroquinolin-4-Ol
CAS No.	1019016-22-8
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	4-Hydroxy-6-bromo-8-fluoroquinoline; 6-Bromo-8-fluoro-4-quinolinol; 8-Fluoro-6-bromoquinolin-4-ol; 6-Bromo-8-fluoro-4-hydroxyquinoline; 6-Bromo-8-fluoroquinolin-4(1H)-one (tautomer); 6-Br-8-F-quinolin-4-ol; 1019016-22-8
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Fluoroquinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.