Description

3-(3,4-Dimethoxyphenyl)-4,5-Dihydroisoxazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoxazoline-carboxylic acid structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Research: Serves as a key scaffold for developing new herbicides and fungicides with specific modes of action.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex heterocyclic compounds for material science and catalysis research.
• Biochemical Probe Development: Employed in medicinal chemistry to create tool compounds for studying enzyme inhibition and receptor binding.
• Fine Chemical Production: Integral in the manufacture of specialty chemicals requiring high-purity, structurally defined intermediates.

Basic Information

Product Name	3-(3,4-Dimethoxyphenyl)-4,5-Dihydroisoxazole-5-Carboxylic Acid
CAS No.	1018143-56-0
Molecular Formula	C12H13NO5
Molecular Weight	251.24 g/mol
Synonyms	5-Isoxazolecarboxylic acid, 4,5-dihydro-3-(3,4-dimethoxyphenyl)-; 3-(3,4-Dimethoxyphenyl)-4,5-dihydroisoxazole-5-carboxylic acid; 4,5-Dihydro-3-(3,4-dimethoxyphenyl)isoxazole-5-carboxylic acid; 5-Carboxy-3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazole; Isoxazoline-5-carboxylic acid derivative; Dihydroisoxazole carboxylic acid intermediate
EINECS	Contact for details

Quality Control

Our production of 3-(3,4-Dimethoxyphenyl)-4,5-Dihydroisoxazole-5-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.