Description

4-Amino-6-Fluoro-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, fluorinated quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. This compound is valued for its unique molecular scaffold, which enables the construction of complex pharmacophores and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Development: Used in creating advanced fungicides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport or emissive layer materials in electronic displays.
• Coordination Chemistry & Catalysis: Serves as a versatile ligand for metal complexes used in catalytic processes.
• Fluorescent Probe Synthesis: Utilized to develop sensitive chemical sensors and bio-imaging agents due to the quinoline fluorophore core.
• Material Science Research: Intermediate for creating specialized polymers and advanced organic frameworks with tailored properties.

Basic Information

Product Name	4-Amino-6-Fluoro-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	1018127-51-9
Molecular Formula	C₁₂H₁₁FN₂O₂
Molecular Weight	234.23 g/mol
Synonyms	Ethyl 4-Amino-6-fluoroquinoline-3-carboxylate; 6-Fluoro-4-aminoquinoline-3-carboxylic acid ethyl ester; 4-Amino-6-fluoro-3-quinolinecarboxylic acid ethyl ester; 4-Amino-6-fluoroquinoline-3-carboxylic acid ethyl ester; AFAQ; 1018127-51-9; Ethyl 4-amino-6-fluoro-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our production of 4-Amino-6-Fluoro-Quinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.