Description

4-(Difluoromethyl)-2-Isopropyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a difluoromethyl group and a fused pyrazolopyridine system, makes it a critical intermediate for the development of novel bioactive molecules. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries seeking to incorporate unique fluorine motifs to modulate the physicochemical properties of their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance lipophilicity, metabolic stability, and biological activity.
• Medicinal Chemistry: Employed as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical space in drug discovery programs.
• Fluorine Chemistry: Acts as a specialized reagent for introducing fluorinated heterocycles into more complex molecular architectures, leveraging the unique electronic properties of fluorine.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects requiring sophisticated fluorinated intermediates.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in heterocyclic and organofluorine chemistry.

Basic Information

Product Name	4-(Difluoromethyl)-2-Isopropyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	1018126-31-2
Molecular Formula	C11H13F2N3O
Molecular Weight	241.24 g/mol
Synonyms	4-(Difluoromethyl)-2-(propan-2-yl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 2-Isopropyl-4-(difluoromethyl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 1018126-31-2; 4-Difluoromethyl-2-isopropyl-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; Pyrazolo[3,4-b]pyridin-6-one, 4-(difluoromethyl)-2,7-dihydro-2-(1-methylethyl)-; SCHEMBL21806227; BCP31134
EINECS	Contact for details

Quality Control

Our production of 4-(Difluoromethyl)-2-Isopropyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical specifications such as assay purity and impurity profiles. Our commitment to consistent quality and traceability supports the rigorous demands of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.