Description

3-(2-Bromo-2-Ethoxycarbonyl-Vinyl)-2-Methyl-Indole-1-Carboxylic Acid tert-Butyl Ester is a sophisticated indole-based building block, specifically engineered for advanced organic synthesis and pharmaceutical research. This compound is valued for its unique molecular architecture, which incorporates a reactive bromovinyl moiety and a protected carboxylic acid, making it a versatile intermediate for constructing complex heterocyclic systems. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole alkaloids and novel drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating specialized organic molecules with potential applications in organic electronics or advanced polymers.
• Academic & R&D: An essential reagent for methodological studies in organic chemistry, particularly in cross-coupling reactions and heterocycle formation.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-(2-Bromo-2-Ethoxycarbonyl-Vinyl)-2-Methyl-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1017968-66-9
Molecular Formula	C19H22BrNO4
Molecular Weight	408.29 g/mol
Synonyms	tert-Butyl 3-[(1E)-2-bromo-2-(ethoxycarbonyl)ethenyl]-2-methyl-1H-indole-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-methyl-3-[(E)-2-bromo-2-(ethoxycarbonyl)vinyl]indole; 3-[(E)-2-Bromo-2-(ethoxycarbonyl)vinyl]-2-methyl-1H-indole-1-carboxylic acid tert-butyl ester; 3-(2-Bromo-2-ethoxycarbonylvinyl)-2-methylindole-1-carboxylic acid tert-butyl ester; Boc-2-Me-3-[(E)-2-Br-2-(COOEt)C=CH]Indole; (E)-tert-Butyl 3-(2-bromo-2-(ethoxycarbonyl)vinyl)-2-methyl-1H-indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 3-(2-Bromo-2-Ethoxycarbonyl-Vinyl)-2-Methyl-Indole-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and should be handled under inert conditions for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.