Description

Ethyl 2-(4-Fluoro-2-Nitrophenyl)-3-Oxo-Butyrate is a high-purity, specialized organic intermediate featuring a nitro-substituted fluorophenyl ring system. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for research and development chemists and process engineers working on novel active ingredients, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and nitro functional groups contribute to biological activity.
• Organic Synthesis Building Block: Serves as a versatile substrate for various organic transformations, including condensation, reduction, and cyclization reactions to create heterocyclic compounds.
• Material Science Research: Investigated for the development of specialty polymers, liquid crystals, or organic electronic materials due to its specific electronic properties imparted by the nitro and fluoro groups.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and pigments where the nitrophenyl moiety acts as a chromophore.

Basic Information

Product Name	Ethyl 2-(4-Fluoro-2-Nitrophenyl)-3-Oxo-Butyrate
CAS No.	1017789-57-9
Molecular Formula	C₁₂H₁₂FNO₅
Molecular Weight	269.23 g/mol
Synonyms	Ethyl 2-(4-Fluoro-2-nitrophenyl)-3-oxobutanoate; 3-Oxobutanoic acid, 2-(4-fluoro-2-nitrophenyl)-, ethyl ester; Ethyl 4-fluoro-2-nitroacetoacetate; Ethyl (4-fluoro-2-nitrobenzoyl)acetate; Butanoic acid, 2-(4-fluoro-2-nitrophenyl)-3-oxo-, ethyl ester; Acetoacetic acid, (4-fluoro-2-nitrophenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Fluoro-2-Nitrophenyl)-3-Oxo-Butyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.